Bank of Clarke will be closed on the following federally recognized holidays:
| HOLIDAYS | 2024 | 2025 |
| New Year's Day | January 1 | January 1 |
| Birthday of Martin Luther King, Jr. | January 15 | January 20 |
| Washington's Birthday | February 19 | February 17 |
| Memorial Day | May 27 | May 26 |
| Juneteenth National Independence Day | June 19 | June 19 |
| Independence Day | July 4 | July 4 |
| Labor Day | September 2 | September 1 |
| Columbus Day | October 14 | October 13 |
| Veterans Day | November 11 | November 11 |
| Thanksgiving Day | November 28 | November 27 |
| Christmas Day | December 25 | December 25 |